Pitt is looking to rebound from its last-second loss to St. John's while West Virginia is coming off a big win against Notre Dame.
The Panthers won round one and will look to make it a regular season sweep against the Mountaineers.
ESPN's Fran Fraschilla breaks down the game with Cardiac Hill
Five questions for each team over at SB Nation Pittsburgh
SB Nation's West Virginia blog, The Smoking Musket